https://mp.weixin.qq.com/s/QZAOQd_XuiXQN92ZpbEN_w

近日，華南農(nóng)大張彤-陳四平團(tuán)隊(duì)在JAFC發(fā)表了題為《Rice Stripe Mosaic Virus Encoded P6 Interacts with Heading Protein OsHAPL1 to Promote Viral Infection》的研究論文，揭示了水稻條紋花葉病毒編碼的P6與抽穗蛋白OsHAPL1相互作用促進(jìn)病毒感染。

水稻條紋花葉病毒（RSMV）是已知的唯一能在自然感染的水稻植株中觀察到的細(xì)胞質(zhì)核糖體病毒。它編碼P6蛋白，誘導(dǎo)感染的水稻植株的抽穗延遲并降低水稻的產(chǎn)量。

在本研究中，作者發(fā)現(xiàn)RSMV的P6與OsHAPL1相互作用，促進(jìn)了OsHAPL1與DTH8之間的相互作用，導(dǎo)致在長(zhǎng)日照條件下水稻抽穗延遲。

此外，OsHAPL1在RSMV感染中扮演雙重角色，既正調(diào)控病毒感染，又負(fù)調(diào)控防御信號(hào)基因的表達(dá)。

這些發(fā)現(xiàn)闡明了一種新的分子機(jī)制，即病毒如何操縱宿主防御系統(tǒng)以增強(qiáng)病毒感染和傳播，為水稻抽穗與病毒抗性途徑之間的交叉互作提供了新見(jiàn)解。

Rice stripe mosaic virus (RSMV) is the sole cytoplasmic rhabdovirus documented in naturally infected rice plants. It encodes P6, which induces delayed heading and reduces yield in infected rice plants. P6 of RSMV interacts with OsHAPL1, facilitating the interaction between OsHAPL1 and DTH8, resulting in delayed rice heading under long day conditions. Additionally, OsHAPL1 plays a dual role in RSMV infection by positively influencing viral infection while negatively regulating the expression of defense signal genes. These findings elucidate a novel molecular mechanism through which a virus manipulates the host defense system to enhance viral infection and transmission, shedding new light on the crosstalk between rice heading and disease resistance pathways.

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